Abstract: Precise quantification of protein-ligand interaction is critical in early-stage drug discovery. Artificial intelligence (AI) has gained massive popularity in this area, with deep-learning ...

A research team at Florida State University's Institute of Molecular Biophysics and Department of Chemistry and Biochemistry has discovered how a protein found in the human body interacts with RNA in ...

ABSTRACT: Protein metabolism constitutes a central regulatory mechanism underpinning normal hepatic physiological function. In Hepatocellular Carcinoma (HCC) and other hepatic pathologies, critical ...

You may feel bewildered today as you move through the usually familiar spheres of your life. When dealing with familiar people, places, and situations, you will likely find yourself growing ever more ...

What’s new in biotech and pharma? Over the last couple of weeks, we’ve seen the unveiling of a spatial assay for visualizing functional protein–protein interactions, an energy dispersive X-ray ...

This valuable study introduces the peptidisc-TPP approach as a promising solution to challenges in membrane proteomics, enabling thermal proteome profiling in a detergent-free system. The concept is ...

Shannon Pruden receives funding from National Institutes of Child Health and Human Development and National Science Foundation. Karinna Rodriguez does not work for, consult, own shares in or receive ...

The ability to grow stem cell-derived biological tissues, such as skin and other organs, in the laboratory holds promise for applications in areas including wound healing and transplants. However, ...

Recently, SandboxAQ launched what it claims is the largest publicly available dataset of protein-ligand pairs with annotated experimental binding potency data. According to the company, the ...